ES Cell Based Gene Overexpression
In addition to pronuclear microinjection, foreign DNA can be introduced into embryonic stem cells (ES cells). Creative Animodel has developed a novel ES cell-based technology that reduces the risks associated with the development of transgenic mouse line by DNA pronuclear random integration. This approach allows the generation of a high number of founders with validated characteristics (no truncated transgene and low, medium or high transgene copy number).
Once your model is generated, Creative Animodel can breed, test, characterize and/or distribute it on your behalf, drawing on six decades of breeding and worldwide distribution experience for an efficient, single-source solution.
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