Preclinical Animal Studies for Rheumatoid Arthritis
Creative Animodel offers the most comprehensive pre-clinical animal testing services for Rheumatoid Arthritis, which includes developing animal models of Rheumatoid Arthritis and lead drug candidates’ toxicity and efficacy evolutions in various species, even in highly challenging NHP. Our experts and scientists has plenty of experience in Rheumatoid Arthritis research and they would work closely with you on every step to choose and develop the most appropriate study plan for Rheumatoid Arthritis. We also provide preclinical service for Rheumatoid Arthritis studies, such as evaluation of RA based on the immunohistochemistry, and assessment of major immune factors such as IL-1, TNF-α, IL-10.
Rheumatoid Arthritis (RA) is a chronic, autoimmune disease in which the body’s immune system mistakenly attacks the joints. This creates chronic inflammation and causes a thicken synovium, swelling and pain around the joints. RA has been a burden to patients since it could lead to pain, disability, and even worse results. It could also affect other parts of the human body including eyes, mouth or lungs. Our experts fully understand the severity of RA and importance of your research. They would choose and develop the best animal models of RA for your research to accelerate the speed of your research.
Creative Animodel provides the following mice models of RA:
• Collagen induced arthritis (CIA) model
• Collagen antibody-induced arthritis (CAIA) model
• Adjuvant induced arthritis (AIA) model
Creative Animodel also provides various preclinical services which includes, but not limited to:
• Body weight measurement
• Immunohistochemically evaluation of the arthritis pathology in joints
• Evaluation of ankle and paw joint swelling
• Assessment of major immune factors such as IL-1, TNF-α
While the cause of RA is not clear yet, it is certain that RA affects plenty of people all over the world. About 0.5 to 1% of adults in the developed world has RA. In the United States, there are 1.5 million people suffering from the disease. Almost three times women have the disease as men. Additionally, middle age around 30 to 60 years old people are more frequent to be affected. In 2013, it has been reported that 38,000 people lost their life because of RA. RA is a series problem threatening people’s health and life. Creative Animodel fully understands the significance of RA related research and the importance of choosing the right model for RA study. We will work side-by-side with you to find the most appropriate mice model meeting your specific aim and to assist you on your way against the disease.
Creative Animodel is a trust worthy partner in design and creation of animal model. Our RA animal model and preclinical services can advance your development of potential therapeutics into clinic efficiently and economically.