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Cell-line-Derived Xenograft Models

Cell line-Derived Xenograft (CDX) model is a well-established and commonly used model type for the research and development of anti-tumor drugs. CDX model still possesses pervasive application at the early stage of in vivo study, due to its user-friendly techniques as well as excellent repeatability. Cancer cell lines are generally inoculated into immune deficient mice subcutaneously, intravenously, or orthotopically. Creative Animodel has established more than 300 well-validated cell-line-derived xenograft (CDX) models as well as luciferase-tagged CDX models to satisfy your in vivo research, of which both solid tumors and precious hematological malignances models are available to customers. Beyond that, Creative Animodel also provides customized services aiming at the personal requirement. Our all-around products involve CDX models construction and delivery, in vivo projects   execution as well as the final results presentation.

Cell-line-Derived Xenograft Models
Cell-line-Derived Xenograft Models

Our CDX models contain the following malignant tumors, but are not limited to:

Hematological Malignances

➤ Acute Lymphoblastic Leukemia ➤ Eosinophilic Leukemia
➤ Acute Monocytic Leukemia ➤ Erythro Leukemia
➤ Acute Myeloid Leukemia ➤ Histiocytic Lymphoma
➤ Acute Myeloblastic Leukemia ➤ Megakaryoblastic Leukemia
➤ Acute Promyelocytic Leukemia ➤ Multiple Myeloma
➤ Chronic Myeloid Leukemia ➤ Non-Hodgkin Lymphoma

Solid Tumors

Our CDX models can be developed into the following types, but are not limited to:

• Subcutaneous Tumor Models

Creative Animodel has established more than 40 hematological malignances subcutaneous xenografts and over 300 solid tumors xenografts to support your preclinical drug efficacy tests.

• Orthotopic Tumor Models

Creative Animodel provides more than 40 orthotopic xenograft models of solid tumors including renal sub-capsule, intracranial, intrasplenic hepatic colonization model, and orthotopic breast tumor models, so as to support your preclinical drug efficacy tests.

• Metastasis Tumor Models

Creative Animodel is currently available for triple negative breast cancer, colorectal cancer metastasis models as well as a systemic distribution model by intracardiac injection of tumor cells.

• Disseminated xenografts

Disseminated xenografts of the referred hematological malignances types in Creative Animodel are also available to customers.

To continually advance with the times, Creative Animodel intends to establish more cell lines which are tumorigenic in mice so as to meet your research needs. Any inquiry, please feel free to contact our customer services.

* For research use only. Not intended for any clinical use.

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