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Constitutive Knockout

Creative Animodel's high-throughput conventional knockout technology enables us to identify and validate the utility of genomic targets within a living model at an extraordinary scale and speed. With Creative Animodel, you get targeted knockouts generated through proven technologies and comprehensive phenotypic data analyzed across consistent protocols.

1 : Subcloning and characterization of the locus of interest
2 : Constitutive knockout vector construction (targeting vector)
3 : Homologous recombination in ES cells
4 : Blastocyst injection and chimera generation
5 : Breeding to the F1 and F2 generation
Constitutive Knockout
Note: Our service offer is flexible. It can be provided on a component basis and adapted to customer requirements.

In the past 20 years, Creative Animodel has been focused on offering custom design and generation of knockout mice for research needs. Germline transmission has been achieved for all knockout projects with competitive timelines.

Our customer service representatives are available 24 hours a day, from Monday to Sunday.
* For research use only. Not intended for any clinical use.

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