Creative Animodel provides comprehensive services for investigating the mechanism of obesity and novel therapeutics to treat obesity. One of the most widely used methods is feeding study includes acute feeding study, sub-chronic and chronic feeding study. Our scientific team has extensive experience in anti-obesity drug development and obesity mechanism investigation. We will assist you on each step of your feeding study for obesity.
Acute feeding study
Acute feeding study is the simplest and most commonly used measurement for screening the anti-obesity potential of a novel drug and for investigation of the mechanism of obesity. Furthermore, acute feeding studies are often used as the initial screen for centrally-acting drugs.
Key features of acute feeding studies:
Behavioural specificity of the reduction in gross food intake can be investigated by:
Sub-chronic and chronic feeding study
To fully evaluate the effects of novel anti-obesity drugs and mechanism on body weight and food and water intake, sub-chronic or chronic feeding studies are commonly utilized. Feeding studies can be performed in normal rat/mouse and obese rat/mouse.
Food intake parameters normally include:
Sub-chronic and chronic feeding studies are customized and can include the following test:
Creative Animodel offers our clients customized feeding studies to meet your specific requirements. Our service also includes advice on experimental design, statistical analysis by a qualified statistician, fully audited data pack and written reports to regulatory standards.