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Dose Ranging Study

Creative Animodel is a global Contract Research Organization (CRO) and has been a trusted partner to leading pharmaceutical, biotechnology and medical device companies as well as academic and government organizations for decades. We offer a full spectrum of preclinical and clinical drug safety evaluation services utilizing state of the art facilities with our highly skilled staffs. With decades of experience in drug toxicology studies, Creative Animodel can deliver robust toxicity testing reports with streamlined turnaround to support customers’ drug development programs.


Dose ranging, known as dose range finding study, is a part of toxicity studies and usually carried out to find out the appropriate dose levels of a test article. The main goal of a dose-ranging study is to estimate the response vs. dose given, so as to analyze the efficacy and safety of a substance or treatment. The information obtained from dose ranging assessments is of great importance in assessing human risk.

Dose Ranging Service at Creative Animodel

Creative Animodel offers in vivo dose ranging service in both rodents and non-rodents with various routes, such as intravenous, subcutaneous, intraperitoneal, ocular or oral administration. Our experienced toxicologists can design and perform dose range finding study that includes dose escalation/maximum tolerated dose study to provide sufficient information to proceed to longer term studies. By measuring the impact at low, intermediate, and high doses as well as placebo groups, our team can demonstrate the no observed adverse effect level (NOAEL), which determines the highest dosage level at which chronic exposure to the substance shows no adverse effects, and the no observed effect level (NOEL), which reveals the dose-response relationship. Additionally, we provide preliminary identification of the target organs of toxicity as well as to dose selection for more definitive studies that are intended to support the clinical trials.

Creative Animodel offers a comprehensive range of services along the entire value chain of pre-clinical drug safety evaluation. With a consultative, flexible, integrated and multi-disciplinary approach, we offer the advice, answers and services to promote your drug to the market.

Our customer service representatives are available 24 hours a day, from Monday to Sunday.

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Creative Animodel

Creative Animodel is a world's leading commercial provider of custom animal model services. We offer top-quality services at unbeatable prices. Our customer service representatives are available 24 hours a day, from Monday to Sunday.

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