Exploratory Non-GLP TK Studies
Creative Animodel has years of experience in the field of drug metabolism and pharmacokinetics. We provide competitively priced non-GLP toxicokinetic services based on several different strategies. Our streamlined procedures and targeted reports allow us to offer credible data with operationally efficient services. Partnering with Creative Animodel will enable you to incorporate the industry's best practices into your drug testing program.
Non-GLP TK Studies
Toxicokinetics (TK) is a combination of pharmacokinetics and toxicology. Based on the principles and methods of pharmacokinetics, TK studies quantificationally discuss in vivo drug absorption, distribution, metabolism and excretion under toxic doses in animals. Research of drug toxicity is helpful for understanding the drug target organs and provides the basis of drug clinical application and drug overdose diagnosis. Although increasing experiments are compliant with GLP standards to ensure the traceability of record and the reliability of results, some TK studies can’t compliant with complete GLP standards at early exploration stage. It is hard to be carried out in accordance with the established plan during the studies and there will always be a process of constantly adjusting. Therefore, Creative Animodel provides exploratory non-GLP TK services involving several different strategies and depending on the scientific questions to be answered.
Our non-GLP protocols are simplified with template of study designs and corresponding abbreviated report format. We focus on preliminary evaluation of key endpoints and use more streamlined designs. Our streamlined processes mean less paperwork and more efficient data collection and review. We have flexible and dedicated staff to perform multiple functions resulting in simplified processes. Client interactions are simplified as well. Review cycles for protocol and report are reduced with preset study designs.
Available Services at Creative Animodel
Our exploratory non-GLP TK studies are conducted in human and various animal species. Typical studies include:
• Safety Pharmacology/Safety Margin
• Human Plasma Limits
• Systemic Exposure Toxicokinetics
• Biological Fluid Concentration
• Tissue Analysis
• High quality management and advanced technology platform
• Comprehensive animal models and preclinical DMPK services
• Rapid turnaround and cost-effective
Creative Animodel is a professional provider of preclinical drug screening and testing services. Our toxicology department holds a team of scientists with rich experience in TK studies. Besides non-GLP TK studies, GLP TK services are also available. We offer rapid turnaround period and high-quality data to promote the development of pharmaceutical industry. If you have any needs, please feel free to contact us.