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Sample Bioanalysis

Creative Animodel has been specialized in sample bioanalysis service for years, supporting our customers in faster informed decision making. Leveraging state-of-the-art techniques and facilities, our scientists have extensive experience in measuring the small and/or large molecular drugs and metabolite concentrations. Our bioanalysis service supports a broad range of samples including plasma, blood, urine, and tissues extract from all stages of drug development. Creative Animodel is one of the leading biotechnology companies and provides precise and timely bioanalytical data in a cost-effective manner.

Bioanalysis is anintegral part of Pharmacokinetic (PK)/Toxicokinetic (TK) characterization of a compound in preclinical and clinical biological samples. Bioanalytical data generated in discovery and preclinical programs are a valuable guide to decision making. Creative Animodel provides a full suite of services, including small molecule bioanalysis, large molecule bioanalysis, as well as method development and validation to accelerate our customers’ research process. Our small molecule bioanalysis provides discovery bioanalysis and regulatory bioanalysis to support PK study, preclinical and clinical samples analysis, tissue distribution study, and pharmacology study. Our large molecule bioanalysis includes drug quantitative measurement, immunogenicity testing, neutralizing antibody screening, and biomarker analysis forbiologics (protein, DNA, RNA) and/or vaccine programs via validated ligand binding assays (LBA). Immunoanalytical techniques are critical for the analysis of large protein molecules and antibody drugs, as well as biosimilars and biomarkers. Creative Animodel offers GLP and non-GLP assays for bioanalysis in supporting different requirements.


Small Molecule Bioanalysis Services
• Method development, transfer, validation
• Drug interaction, TK, PK
• Early discovery bioanalysis (non-GLP)
• High throughput analysis of biological samples for preclinical and clinical studies

Large Molecule Bioanalysis Services
• Immunogenicity assays
• Ligand binding assays for PK/TK
• qPCR or NGS based PK/TK for DNA or RNA drugs
• Enzyme kinetic assays
• Biomarker service for drug development
• Sample quantification

Instruments for Small Molecule Bioanalysis
• LC-MS/MS instruments – Applied Biosystems SCIEX API 3000, 4000 and 5000s
• HPLC Shimadzu UFLC / LC-20 Systems
• UFLC Shimadzu LFLC/HPLC LC-30XR Systems (19,000 PSI)

Technologies for Large Molecule Bioanalysis
• Enzyme immunoassay (EIA)
• Radioimmunoassay
• Surface plasmon resonance
• Cell-based assays
• qPCR or NGS

• High throughput automated sample preparation.
• Standard operating procedures (SOPs)
• Rapid turnaround time
• Fit-for-purpose measurement methods.
• State-of-the-art equipment

Creative Animodel is a professional provider of sample bioanalysis service for small molecule and large molecule. We are dedicated to every aspect of sample bioanalysis including sample preparation and data storage, key factors to guarantee high-quality sample bioanalysis result. Our qualified scientists with expertise in sample bioanalysis have extensive problem-solving skills to help you accurately quantify your compound concentration in different matrices. As your partner, we work to develop the most efficient and accurate methods, removing barriers and accelerating your development timeline. If you have any questions, please feel free to contact us.

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45-1 Ramsey Road, Shirley, NY 11967, USA 1-631-614-7828 1-631-372-1052 Europe 44-207-097-1828

Creative Animodel

Creative Animodel is a world's leading commercial provider of custom animal model services. We offer top-quality services at unbeatable prices. Our customer service representatives are available 24 hours a day, from Monday to Sunday.

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