Creative Animodel is an experienced contract research organization which provides pharmacological services of oncology. Based on our state-of-the-art technology, we can offer comprehensive information for researching therapeutic and preventative treatments for cancer in a time-saving and cost-efficient manner.
An Overview of Oncology
Oncology is a branch of medicine that is concerned with the prevention, diagnosis and treatment of cancer. Cancer is a name which is given to a collection of related diseases. It is a complex and heterogenic genetic disease involving an almost infinite number and a combination of cellular and molecular perturbations. Many cancers form solid tumors which are masses of tissue, while cancers of blood do not form solid tumors, such as leukemia. Generally, the types of cancer are named for the tissues or organs where cancer from, and there are over 100 different types of cancers.
Cancer is a complex life-threatening disease with patients having a poor prognosis and significantly reduced life expectancy. It is believed that the successful development of new treatments for cancer can have an immediate impact on patient survival. We can provide different cancer models for your cancer studies as well as new anti-cancer drugs and treatment development.
Available Oncology Services
Cell Line-Derived Xenograft (CDX) Models
CDX models are established by inoculating tumor cell lines into immunodeficient mice or rats. Numerous validated and well-characterized CDX models are available at Creative Animodel. Based on these diverse models, we can provide reliable assays to meet various demands of oncology studies and promote anti-tumor drugs development.
Patient-Derived Xenograft (PDX) Models
PDX is created by transferring primary tumors from the patient into an immunodeficient mouse or rat. With a wide variety of PDX models, Creative Animodel can provide various assays to facilitate your drug discovery and development. There are subcutaneous, orthotopic and disseminated models available. And our PDX models cover most cancer types.
Genetically Modified Models
Creative Animodel can provide genetically modified models by different technologies, such as pronuclear microinjection, knock-in, knock-down, knock-out and CRISPR/Cas9. We can offer customized genetically modified models depending on clients’ needs.
Humanized Immune-Checkpoint Mice Models
Humanized immune checkpoint mice models can obtain human knock-in immune checkpoint genes to test drugs that target human immune cells. Based on our humanized immune checkpoint mice models, Creative Animodel can provide different assays. Our models have a stable genetic background and available for many immune checkpoint proteins, such as PD-1, CTLA-4, PD-L1, CD137.
Other Oncology Models
In addition to these models above, Creative Animodel can provide other oncology models which are related to cancer metastasis, cancer syndrome, as well as immuno-oncology research.
Service Platforms for Xenograft Models
Taking advantages of professional experts and diverse models, Creative Animodel can offer in vivo
efficacy testing, PDX characterization as well as tumor biomarker selection and validation for our clients.
Creative Animodel can provide comprehensive pharmacological services of oncology. We have a team of scientists with profound pharmaceutical knowledge to support you in all aspects of new drug discovery and development. Our reliable and high-quality results can help you make the right decision to accelerate your researches. If you have any questions, please feel free to contact us.