Creative Animodel is a professional provider that focuses on in vivo pharmacology. We have over 150 human disease models which are valuable tools to evaluate new small molecules and biologics, siRNA and liposomal formulated drugs. With rich-experienced scientists and state-of-the-art technique platforms, we can provide various eye disease models to conduct pre-clinical drug screening and treatment evaluation experiments, as well as fundamental studies.
• Diabetic Retinopathy models
Diabetic retinopathy (DR), a major complication of diabetes, is one of the leading causes of blindness worldwide. Our non-human primate model is the highest transnational model for novel drug development for it replicates the human ophthalmic pathologies.
• Glaucoma models
Glaucoma is not one single disease entity, but comprises a heterogeneous group of disorders, which makes drug discovery difficult. Creative Animodel has developed non-human primate models of glaucoma for the study of the pathophysiology of human glaucoma and drug discovery.
• Cataract models
Cataract is a clouding of the lens in the eye which leads to a decrease in vision. Our cataract models can be classified into three categories: inducible cataract models, hereditary models and knockout animal models.
• Age-related macular degeneration models
Age-related macular degeneration (AMD) is a progressive condition of the retinal pigment epithelium, its supporting basement membrane and the overlying photoreceptor layer. Creative Animodel has both spontaneous dry AMD and laser-induced choroidal neovascularization (CNV) models.
• Experimental Autoimmune Uveoretinitis (EAU) Models
Experimental autoimmune uveoretinitis (EAU) in rodents can imitate a prototypic T cell-mediated autoimmune disease that targets the neural retina and related tissues. The model is used to represent human sight-threatening inflammatory eye diseases that are believed to have an autoimmune etiology.
• Extensive experience of optical coherence tomography (OCT) and fundus photography (FP)
• Diverse animal models including mice, rats, rabbits, pigs and non-human primates
• Customized model development to meet customers’ special requirements
• Competitive price and fast turnaround time
Creative Animodel offers end-to-end validated pre-clinical models and related services of pharmacology and toxicology. We will keep close communication and coordination with you during the period of both model establishment and drug assessment. Therefore, we could be the best partner of your research to understand the pathogenesis of diseases in human, defining novel therapeutic targets and screening drugs. If you have any questions, please don’t hesitate to contact us.