Creative Animodel is an ideal partner in in vivo pharmacology research during the drug discovery and development process. With the state-of-the-art facilities and technologies, we have strong expertise in developing vaginitis models suited for understanding of vaginitis pathology and investigating new drugs’ efficacy.
Overview of Vaginitis
Vaginitis is a common female disorder manifested by symptoms that can include vulvovaginal itching, burning, malodor, and abnormal discharge. It is a condition responsible for 10 million office visits annually and health care costs are estimated at $500 million to $1 billion annually. More than 10% of ambulatory visits of women’s health care are made by patients with vaginitis.
The most common infectious causes of vaginitis are bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and trichomoniasis. Bacterial vaginosis is the most common vaginal infection, responsible for 40% to 50% of total numbers. Bacterial vaginosis represents a microbial imbalance of the vaginal ecosystem, characterized by depletion of the normally dominant hydrogen peroxide-producing lactobacilli and overgrowth of certain anaerobic or facultative aerobic organisms. Candida vaginitis is the second most common cause of vaginal infections. It is caused by Candida albicans in 70% to 90% of cases. A frothy, malodorous, yellow-green discharge is a common complaint of patients infected with Trichomonas vaginalis (TV). TV is a unicellular, ﬂagellated protozoan and is the third most common cause of infectious vaginitis.
Our Vaginitis Models
The development of easily manageable, reproducible, and economically viable animal models of vaginitis is highly important. With years of experience, we can provide professional vaginitis models to advance the understanding of pathology as well as discover effective therapeutics that prevent the vaginitis processes.
Creative Animodel has spent decades of efforts to provide professional pharmacology services in human diseases. Our experienced experts are glad to assist you with our strong knowledge and analytical skills. If you have any other questions or specific requirements, please do not hesitate to contact us.
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2. Carrara M A,. et al. A new model of vaginal infection by Candida albicans in rats. Mycopathologia. 2010, 170(5):331.
3. Cobo E R,. et al. Murine models of vaginal trichomonad infections. American Journal of Tropical Medicine & Hygiene. 2011, 85(4):667.